| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| Until recently , most studies of the two pathways have solely focused on the core signaling complexes that are shared by the different receptors : death inducing complexes containing the cysteine proteases caspase 8 and caspase 10 , bound to the adapter protein MORT1 / FADD ( mediator of receptor induced toxicity / Fas associated DD protein ) , and the NF kappaB activating complex , composed of the protein kinases IKK 1 ( IkappaB kinase 1 ) and IKK 2 ( IkappaB kinase 2 ) and the regulatory subunit NEMO ( NF kappaB essential modulator ; the ' IKK signalosome ' ) . ^^^ |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| The effects of age and CR on muscle mass , myocyte area , fiber number , myocyte TNF alpha expression , plasma TNF alpha levels , and specific elements linked with the TNF alpha signaling cascade ( TNF R 1 , IKKgamma , IkappaBalpha , p 65 , NF kappaB binding activity , FADD , caspase 8 , and DNA fragmentation ) were investigated in soleus ( predominately Type 1 fiber ) , and superficial vastus lateralis ( SVL , predominately Type 2 fiber ) , of 6 month old ad libitum fed ( 6AL ) , 26 month old ad libitum fed ( 26AL ) , and 26 month old calorie restricted ( 26CR ) male Fischer 344 rats ( CR = 40 % restriction compared with ad libitum ) . ^^^ |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| The secondary complex retained the DISC components FADD and caspase 8 , but recruited several factors involved in kinase activation by TNF , namely , RIP 1 , TRAF 2 , and NEMO / IKKgamma . ^^^ |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q9Y6K9 |
Pubmed |
SVM Score :0.0 |
| NA |
|