| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| This ERE bound ERalpha and ERbeta , and formed a complex that included SRC 1 , but not CBP , N CoR or SMRT . ^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.55640659 |
| CHO K 1 cells transfected with ERalpha or ERbeta show ERE sequence dependent differences in the functional interaction of ERalpha and ERbeta with coactivators steroid receptor coactivator 1 ( SRC 1 ) , SRC 2 ( glucocorticoid receptor interacting protein 1 ( GRIP 1 ) ) , SRC 3 amplified in breast cancer 1 ( AIB 1 ) and ACTR , cyclic AMP binding protein ( CBP ) , and steroid receptor RNA activator ( SRA ) , corepressors nuclear receptor co repressor ( NCoR ) and silencing mediator for retinoid and thyroid hormone receptors ( SMRT ) , and secondary coactivators coactivator associated arginine methyltransferase 1 ( CARM 1 ) and protein arginine methyltransferase 1 ( PRMT 1 ) . 0.55640659^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| To obtain some clue to these roles , we screened the expression levels of ER alpha , ER beta , coactivators ( SRC 1 , TIF 2 , AIB 1 , CBP , and P / CAF ) and corepressors ( N CoR and SMRT ) in 6 normal mammary glands , 6 intraductal carcinomas , 22 invasive ductal carcinomas , and 7 breast cancer cell lines using a multiplex reverse transcription PCR . ^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| In both cell lines ( MCF 7 and T47D ) and in primary breast cancer cell cultures , beta estradiol up regulated ER beta and coregulator protein expression and increased ER alpha / ER beta interaction with the estrogen response element ( ERE ) . 4 Hydroxy tamoxifen ( 4 OHT ) increased ER alpha and silencing mediator for retinoid and thyroid receptors ( SMRT ) expression and increased ER ERE binding . ^^^ Conversely , in cells treated with 4 OHT , ER alpha and ER beta bound SMRT . ^^^ Differential recruitment of SRC 1 and SMRT by ER alpha and ER beta in the presence of beta estradiol and 4 OHT may be central to the response of the tumor to endocrine treatment . . ^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| In this work we have determined the role of the 26S proteasome in the regulation of the content of progesterone receptors ( PR A and PR B ) , estrogen receptors ( ER alpha and ER beta ) , the coactivator SRC 1 and the corepressor SMRT in the rat brain during the estrous cycle . ^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| Expression levels of oestrogen receptors ( ERalpha , ERbeta ) , cofactors AIB 1 , RIP 140 , SMRT and the Fas associated protein tyrosine phophatase 1 ( FAP 1 ) genes were evaluated in breast , endometrial and ovarian cancer cell lines and in three ERalpha positive and three ERalpha negative breast cancer tumours . ^^^ |
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| Interacting proteins: Q92731 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| The aim of the study was to test the hypothesis that expression of retinoid receptors ( RARalpha , RARbeta , RARgamma ) , rexinoid receptors ( RXRalpha , RXRbeta ) , thyroid hormone receptors ( TRalpha , TRbeta ) , estrogen receptors ( ERalpha , ERbeta ) , nuclear receptor coregulators ( N CoR , SRC 1 , SMRT ) , and in addition type 1 iodothyronine 5 ' deiodinase ( 5 ' DI ) , EGFR and erb B2 / neu would be different in mammary postlactating tissue in comparison with that of nonlactating mammary gland . ^^^ Using RT PCR , we have shown that expression of RARalpha , RXRalpha , TRalpha , ERalpha , ERbeta , N CoR , SRC 1 , SMRT and EGFR in rat was significantly increased in postlactating mammary gland when compared to that of nonlactating mammary tissue . ^^^ |
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