| Interacting proteins: Q8WUI4 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| In contrast to this model , a two hybrid screen on SMRT interacting proteins resulted in the isolation of the recently described HDAC 5 and a new family member termed HDAC 7 . ^^^ |
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| Interacting proteins: Q8WUI4 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| We provide evidence that the transcriptional corepressors SMRT and N CoR could serve as critical mediators of HDAC 7 activity by binding class 2 HDACs and HDAC 3 by two distinct repressor domains . ^^^ Different class 2 HDACs reside in the cell nucleus in stable and autonomous complexes with enzymatic activity , but the enzymatic activities associated with HDAC 7 and HDAC 4 rely on shared cofactors , including HDAC 3 and SMRT / N CoR . . ^^^ |
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