| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.53982834 |
| In yeast two hybrid assays , the SMRT aa 1291 to 1495 domain interacted with SKIP and SMRT aa 1291 to 1495 colocalized with SKIP within the nuclei of cotransfected cells . 0.53982834^^^ |
|
| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.0 |
| Protein protein interaction assays demonstrated contacts between SKIP and the SMRT , CIR , Sin3A , and HDAC 2 proteins of the CBF 1 corepressor complex . ^^^ A model is presented in which EBNA 2 competes with the SMRT corepressor complex for contacts on SKIP and CBF1 . . ^^^ |
|
| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.0 |
| Protein protein interaction assays demonstrated interaction between SKIP and the corepressor SMRT . ^^^ In competition binding experiments SMRT displaced NotchIC from CBF 1 and from SKIP . ^^^ The results suggest a model in which NotchIC activates responsive promoters by competing with the SMRT corepressor complex for contacts on both CBF 1 and SKIP . . ^^^ |
|
| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.0 |
| In cotransfection experiments , SHARP mediated repression was sensitive to the HDAC inhibitor TSA and facilitated by SKIP , a highly conserved SMRT and RBP Jkappa interacting protein . ^^^ |
|
| Interacting proteins: Q9Y618 and Q13573 |
Pubmed |
SVM Score :0.0 |
| Ski interacting protein ( SKIP ) , a vitamin D receptor ( VDR ) coactivator , also functions as a repressor in Notch signalling in association with the corepressor SMRT . ^^^ The corepressors N CoR and SMRT and the coregulator p 300 interacted with SKIP through the same N terminal region ( 1 200 aa ) . ^^^ |
|