| Interacting proteins: P35869 and Q9Y618 |
Pubmed |
SVM Score :0.80023881 |
| This study investigates physical and functional interactions of the AhR complex with a prototypical coactivator ( estrogen receptor associating protein 140 , ERAP 140 ) and corepressor ( silencing mediator for retinoic acid and thyroid hormone receptor , SMRT ) for ER and other members of the nuclear receptor superfamily . 0.80023881^^^ |
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| Interacting proteins: P35869 and Q9Y618 |
Pubmed |
SVM Score :0.51880233 |
| Association of SMRT with the AhR : ARNT : DNA complex was not detected by GST pull down or gel retardation assays . 0.51880233^^^ Furthermore , the interaction between SMRT and the AhR may have implications in pathways other than the AhR signaling pathway . . 0.50386112^^^ |
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| Interacting proteins: P35869 and Q9Y618 |
Pubmed |
SVM Score :1.105275 |
| AhR was shown to be involved in a mutual antagonism with RARalpha corepressor SMRT ( silencing mediator of retinoid and thyroid receptors ) . 1.105275^^^ |
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| Interacting proteins: P35869 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| Moreover , a physical interaction between AhR and the RAR corepressor SMRT has been described in vitro . ^^^ Using the corepressor inhibitor TSA , transfected cells with SMRT cDNA , and coimmunoprecipitation experiments , we demonstrated that RA addition repressed AhR function through a marked AhR / SMRT physical interaction . ^^^ Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor . ^^^ |
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