| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.78470538 |
| RAR alpha strongly interacts with SMRT and can repress target gene transcription , whereas RAR beta and gamma interact with SMRT only weakly and fail to repress . 0.78470538^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.62596554 |
| These differing transcriptional properties appear to reflect the differing abilities of the three RAR isotypes to interact with the SMRT ( silencing mediator of retinoic acid and thyroid hormone receptor ) corepressor protein : RARalpha binds to SMRT strongly both in vitro and in vivo , whereas RARbeta and RARgamma interact only weakly with SMRT . 0.62596554^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| The aim of the study was to test the hypothesis that expression of retinoid receptors ( RARalpha , RARbeta , RARgamma ) , rexinoid receptors ( RXRalpha , RXRbeta ) , thyroid hormone receptors ( TRalpha , TRbeta ) , estrogen receptors ( ERalpha , ERbeta ) , nuclear receptor coregulators ( N CoR , SRC 1 , SMRT ) , and in addition type 1 iodothyronine 5 ' deiodinase ( 5 ' DI ) , EGFR and erb B2 / neu would be different in mammary postlactating tissue in comparison with that of nonlactating mammary gland . ^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| We investigated the expression of the co repressor ( SMRT ) and co activator ( Trip 1 ) for retinoid and thyroid hormone receptors in several neuroectodermal tumour cell lines , and its modulation by all trans retinoic acid , as well as by synthetic agonists , for RAR alpha , RAR beta , RAR gamma and RXR . ^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| We also studied RARE binding properties and interactions between nuclear corepressor SMRT and various fusion proteins in response to ATRA . ^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| Thus , STAT5b RARalpha contributes to myeloid maturation arrest by binding to RARE as either a homodimer or as a heterodimer with RXRalpha resulting in the recruitment of SMRT and inhibition of RARalpha / RXRalpha transcriptional activity . ^^^ |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10826 and Q9Y618 |
Pubmed |
SVM Score :0.0 |
| NA |
|