Interacting proteins: Q9Y5U5 and Q12933 |
Pubmed |
SVM Score :0.0 |
AITR associates with TRAF 1 ( TNF receptor associated factor 1 ) , TRAF 2 , and TRAF 3 , and induces nuclear factor ( NF ) kappaB activation via TRAF 2 . ^^^ |
|
Interacting proteins: Q9Y5U5 and Q12933 |
Pubmed |
SVM Score :0.0 |
Yeast two hybrid assays and studies in HEK 293 cells and primary lymphocytes indicated interactions between TRAF 2 and GITR mediated by acidic residues in the cytoplasmic domain of the receptor . ^^^ Interestingly , in contrast with its effects on signaling triggered by other TNFRs , our functional studies revealed that TRAF 2 plays a novel inhibitory role in GITR triggered NF kappaB activation . . ^^^ |
|
Interacting proteins: Q9Y5U5 and Q12933 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q9Y5U5 and Q12933 |
Pubmed |
SVM Score :0.0 |
NA |
|