| Interacting proteins: Q86XX4 and Q9Y3R0 |
Pubmed |
SVM Score :0.91552042 |
| GRIP 1 can physically interact with Fras 1 and is required for the localization of Fras 1 to the basal side of cells . 0.91552042^^^ |
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| Interacting proteins: Q86XX4 and Q9Y3R0 |
Pubmed |
SVM Score :0.0 |
| Furthermore , Frem 1 appears to act as a dermal mediator of basement membrane adhesion , apparently independently of the other known `` blebs ' ' proteins Fras 1 and Grip 1 . ^^^ Unlike both Fras 1 and Grip 1 mutants , collagen 6 and Fras 1 deposition in the basement membrane is normal , indicating that the protein plays an independent role in epidermal differentiation and is required for epidermal adhesion during embryonic development . . ^^^ |
|
| Interacting proteins: Q86XX4 and Q9Y3R0 |
Pubmed |
SVM Score :0.0 |
| This coordinated reduction in basement membrane deposition was also observed in another Fraser syndrome model mouse , in which GRIP 1 , a Fras 1 and Frem 2 interacting adaptor protein , is primarily affected . ^^^ |
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