| Interacting proteins: Q13045 and Q9Y3R0 |
Pubmed |
SVM Score :0.0 |
| Fli 1 bound to CARM 1 , GRIP 1 , and NRs and cooperated synergistically with CARM 1 and GRIP 1 to enhance NR function . ^^^ The synergy between GRIP 1 , CARM 1 , and Fli 1 required the methyltransferase activity of CARM 1 . ^^^ The C terminal AD 1 ( binding site for p300 / CBP ) and AD 2 ( binding site for CARM 1 ) activation domains of GRIP 1 contributed to the synergy but were less stringently required than the N terminal region of GRIP 1 , which is the binding site for Fli 1 . ^^^ |
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| Interacting proteins: Q13045 and Q9Y3R0 |
Pubmed |
SVM Score :0.0 |
| One important coactivator complex includes a p 160 coactivator ( GRIP 1 , SRC 1 , or ACTR ) and its downstream coactivators ( e . g . , p 300 , CARM 1 , CoCoA , and Fli 1 ) , which contribute to transcriptional activation by protein acetylation , protein methylation , and protein protein interactions . ^^^ |
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