| Pontin 52 and reptin 52 function as antagonistic regulators of beta catenin signalling activity . ^^^ Highly homologous to Pontin 52 , Reptin 52 likewise binds beta catenin and TBP . ^^^ These results indicate that the opposite action of Pontin 52 and Reptin 52 on beta catenin mediated transactivation constitutes an additional mechanism for the control of the canonical Wingless / Wnt pathway . . ^^^ |