| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| TGF beta induces fibronectin synthesis through a c Jun N terminal kinase dependent , Smad 4 independent pathway . ^^^ Finally , we show that TGF beta induced fibronectin synthesis is independent of Smad 4 . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| Ten genes [ macrophage inhibitory cytokine 1 , CGD , fibronectin ( FN ) , hypoxia inducible factor 1 , Fc epsilon receptor gamma chain , lactate dehydrogenase A , HLA DBP 1 , AH receptor , tissue inhibitor of metalloproteinase ( TIMP 1 ) , and glycyl tRNA synthetase ] were found to be up regulated > 2 fold in 40 100 % of cancers , whereas 9 genes ( GADD 153 , polykystic kidney disease 1 , CYR 61 , DPC 4 , HBA 1 , gravin , DLG 3 , protein tyrosine phosphatase sigma , and heterochromatin protein 1 homologue alpha ) were down regulated to < 50 % of their normal levels in 40 94 % of cases . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| Expression of Smad 4 in the FaDu cell line partially restores TGF beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| The ECM genes , alpha 1 type 1 collagen ( COL1A1 ) , plasminogen activator inhibitor 1 ( PAI 1 ) and fibronectin ( FN ) were assessed in wild type mesangial cells and stably transfected Smad 4 DN cell lines in the absence and presence of TGF beta . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| Aortic TGF beta 1 type 2 receptor ( TbetaRII ) , its downstream molecules p similar to mad mother against decapentaplegic ( SMAD ) 2 / 3 and SMAD 4 , fibronectin , and collagen also increased with age . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| Dominant negative Smad 4 did not affect the FN mRNA increase induced by TGF beta 1 and high glucose . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| Although T 3 induces the expression of TGF beta , neither wild type nor dominant negative Smad 3 or Smad 4 over expression affected the activation of FN by T 3 . ^^^ |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQS6 and Q13485 |
Pubmed |
SVM Score :0.0 |
| NA |
|