| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| Northern analysis indicates that transcription variant jip 1 is expressed in brain and kidney and transcription variants jip 2 and jip 3 are specifically expressed in brain . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| The association is specific to JIP 3 , as the two other JIPs , JIP 1 and JIP 2 , failed to bind TLR 4 . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| The c Jun NH 2 terminal kinase ( JNK ) interacting protein ( JIP ) group of scaffold proteins ( JIP 1 , JIP 2 , and JIP 3 ) can interact with components of the JNK signaling pathway and potently activate JNK . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| Cross talk between JIP 3 and JIP 1 during glucose deprivation : SEK 1 JNK2 and Akt 1 act as mediators . ^^^ In the present study , we reveal that two scaffolding proteins , JIP 1 and JIP 3 , have a cross talk that leads to the regulation of the ASK 1 SEK1 JNK signal during glucose deprivation . ^^^ Taken together , our data demonstrate that cross talk between JIP 3 and JIP 1 is mediated through SEK 1 JNK2 and Akt1 . . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| The axon guidance defect of the telencephalic commissures of the JSAP 1 deficient brain was partially rescued by the transgenic expression of JIP 1 . ^^^ The axon guidance defect of the corpus callosum in the jsap 1 / brain was correlated with the misplacement of glial sling cells , which reverted to their normal position after the transgenic expression of JNK interacting protein 1 ( JIP 1 ) . ^^^ The transgenic JIP 1 partially rescued the axon guidance defect of the corpus callosum and the anterior commissure of the jsap 1 / brain . ^^^ These results suggest that JSAP 1 is required for the axon guidance of the telencephalic commissures and the distribution of cellular protein ( s ) along axons in vivo , and that the signaling network organized commonly by JIP 1 and JSAP 1 regulates the axon guidance in the developing brain . . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| The roles of JSAP 1 and JIP 1 in cell adhesion and spreading were examined using mouse embryonic fibroblasts ( MEFs ) deficient in JIP 1 ( JIP 1 KO ) , JSAP 1 ( JSAP 1 KO ) , and in both JIP 1 and JSAP 1 ( double KO ) , and by using their wild type . ^^^ The cellular properties of double KO MEFs and JIP 1 KO MEFs were similar to those of JSAP 1 KO MEFs and wild type MEFs , respectively . ^^^ |
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| Interacting proteins: Q9UPT6 and Q9UQF2 |
Pubmed |
SVM Score :0.0 |
| NA |
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