| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.92910075 |
| We show that hEXO 1 colocalizes with proliferating cell nuclear antigen ( PCNA ) at DNA replication sites and that the C terminal region of hEXO 1 is sufficient for this localization . 0.92910075^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.64176394 |
| EXOI interacts with PCNA . 0.64176394^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| A number of other proteins have been implicated in MMR , including DNA polymerase delta , RPA ( replication protein A ) , PCNA ( proliferating cell nuclear antigen ) , RFC ( replication factor C ) , Exonuclease 1 , FEN 1 ( RAD 27 ) and the DNA polymerase delta and epsilon associated exonucleases . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| Additional factors with a possible function in eukaryotic MMR are PCNA , EXO 1 , and the DNA polymerases delta and epsilon . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| The reconstituted system includes MutSalpha or MutSbeta , MutLalpha , RPA , EXO 1 , HMGB 1 , PCNA , RFC , polymerase delta , and ligase 1 . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| Bidirectional mismatch repair directed by a strand break located 3 ' or 5 ' to the mispair has been reconstituted using seven purified human activities : MutSalpha , MutLalpha , EXOI , replication protein A ( RPA ) , proliferating cell nuclear antigen ( PCNA ) , replication factor C ( RFC ) and DNA polymerase delta . ^^^ In addition to DNA polymerase delta , PCNA , RFC , and RPA , 5 ' directed repair depends on MutSalpha and EXOI , whereas 3 ' directed mismatch correction also requires MutLalpha . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| We investigated 44 single nucleotide polymorphisms ( SNPs ) in 20 DNA repair genes including nucleotide excision repair ( NER ) genes XPA , ERCC 1 , ERCC2 / XPD , ERCC4 / XPF and ERCC5 / XPG ; base excision repair ( BER ) genes APE1 / APEX , OGG 1 , MPG , XRCC 1 , PCNA , POLB , POLiota , LIG 3 and EXO 1 ; double strand break repair ( DSB R ) genes XRCC 2 , XRCC 3 , XRCC 9 , NBS 1 and ATR ; and direct damage reversal ( DR ) gene MGMT / AGT . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| These studies have shown that PCNA interacts directly with several MMR components , including MSH 3 , MSH 6 , MLH 1 , and EXO 1 . ^^^ |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQ84 and P12004 |
Pubmed |
SVM Score :0.0 |
| NA |
|