| Interacting proteins: P83436 and Q9UP83 |
Pubmed |
SVM Score :0.0 |
| Our results suggest that COG 4 serves as a core component of the complex by interacting directly with COG 1 , COG 2 , COG 5 , and COG 7 . ^^^ Incorporation of COG 6 into the complex depends on the concerted interaction of both COG 5 and COG 7 , whereas optimal incorporation of COG 8 depends on the concerted interaction of COG 5 , COG 6 , and COG 7 . ^^^ |
|
| Interacting proteins: P83436 and Q9UP83 |
Pubmed |
SVM Score :0.0 |
| Genetic analysis of the subunit organization and function of the conserved oligomeric golgi ( COG ) complex : studies of COG 5 and COG 7 deficient mammalian cells . ^^^ We have analyzed the structure and function of COG using Cog 1 or Cog 2 null Chinese hamster ovary cell mutants , fibroblasts from a patient with Cog 7 deficient congenital disorders of glycosylation , and stable Cog 5 deficient HeLa cells generated by RNA interference . ^^^ Only one or two of the seven Cog 1 or Cog 2 dependent Golgi membrane proteins called GEARs are also sensitive to Cog 5 or Cog 7 deficiency , indicating that the COG subunits play distinctive roles in controlling Golgi structure and function . . ^^^ |
|
| Interacting proteins: Q9UP83 and P83436 |
Pubmed |
SVM Score :0.0 |
| Our results suggest that COG 4 serves as a core component of the complex by interacting directly with COG 1 , COG 2 , COG 5 , and COG 7 . ^^^ Incorporation of COG 6 into the complex depends on the concerted interaction of both COG 5 and COG 7 , whereas optimal incorporation of COG 8 depends on the concerted interaction of COG 5 , COG 6 , and COG 7 . ^^^ |
|
| Interacting proteins: Q9UP83 and P83436 |
Pubmed |
SVM Score :0.0 |
| Genetic analysis of the subunit organization and function of the conserved oligomeric golgi ( COG ) complex : studies of COG 5 and COG 7 deficient mammalian cells . ^^^ We have analyzed the structure and function of COG using Cog 1 or Cog 2 null Chinese hamster ovary cell mutants , fibroblasts from a patient with Cog 7 deficient congenital disorders of glycosylation , and stable Cog 5 deficient HeLa cells generated by RNA interference . ^^^ Only one or two of the seven Cog 1 or Cog 2 dependent Golgi membrane proteins called GEARs are also sensitive to Cog 5 or Cog 7 deficiency , indicating that the COG subunits play distinctive roles in controlling Golgi structure and function . . ^^^ |
|