Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Our data suggest a model whereby taz 1 ( ) telomeres are exposed to the prevailing mode of DNA repair , which is dictated by the cell cycle . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Moreover , in taz 1 disrupted cells , molecular fusion of Rap 1 with the Taz 1 DNA binding domain recovers telomere clustering and largely complements defects in meiosis , indicating that telomere localization of Rap 1 is a key requirement for meiosis . . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
On the other hand , human TRF 1 and TRF 2 , as well as their fission yeast homolog , Taz 1 , directly bind to telomeric DNA and negatively regulate telomere length . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
On the basis of telomere lengths of mutant combinations of various checkpoint related proteins ( Rad 1 , Rad 3 , Rad 9 , Rad 17 , Rad 26 , Hus 1 , Crb 2 , Chk 1 , Cds 1 ) , Tel 1 , a telomere binding protein ( Taz 1 ) , and DNA repair proteins ( Ku 70 , Rad 32 ) , we conclude that Rad3 / Rad26 and Tel1 / Rad32 represent two pathways required to maintain telomeres and prevent chromosome circularization . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Interestingly , this telomere association of Pku proteins is independent of Taz 1 , a telomeric DNA binding protein . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
The telomere protein Taz 1 is required to prevent and repair genomic DNA breaks . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Taz 1 is recruited to subtelomeres by an autonomous element present in subtelomeric DNA , thus in a genetic mechanism . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
The fission yeast ortholog of human TRF1 / 2 , Taz 1 , binds telomeric DNA and regulates numerous aspects of telomere function . ^^^ |
|
Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Semi conservative DNA replication through telomeres requires Taz 1 . ^^^ |
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Interacting proteins: Q99592 and Q9UBC3 |
Pubmed |
SVM Score :0.0 |
Here , we show that Dnmt3a associates with RP 58 , a DNA binding transcriptional repressor protein found at transcriptionally silent heterochromatin . ^^^ |
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