Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.6099625 |
Ataxin 2 interacts with ataxin 2 binding protein 1 ( A2BP1 ) , a member of a novel family of putative RNA binding proteins . 0.6099625^^^ |
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Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.68129337 |
However , ATX 2 interacts with A2BP1 , a protein containing an RNA recognition motif , and the existence of an interaction motif for the C terminal domain of the poly ( A ) binding protein ( PABC ) as well as an Lsm ( Like Sm ) domain in ATX 2 suggest that ATX 2 like its yeast homolog Pbp 1 might be involved in RNA metabolism . 0.68129337^^^ |
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Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.0 |
Using the yeast two hybrid system , we identified a novel protein , A2BP1 ( ataxin 2 binding protein 1 ) which binds to the C terminus of ataxin 2 . ^^^ By immunocfluorescent staining , A2BP1 and ataxin 2 were both localized to the trans Golgi network . ^^^ Immunocytochemistry showed that A2BP1 was expressed in the cytoplasm of Purkinje cells and dentate neurons in a pattern similar to that seen for ataxin 2 labeling . ^^^ Western blot analysis of subcellular fractions indicated enrichment of A2BP1 in the same fractions as ataxin 2 . ^^^ |
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Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.0 |
It interacts at its C terminus with ataxin 2 binding protein 1 , A2BP1 . ^^^ Previous studies in other model systems had implicated the orthologs of ataxin 2 and A2BP1 in development . ^^^ |
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Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.0 |
In mammals , there are at least two Fox 1 related genes , ataxin 2 binding protein 1 ( A2BP1 ) / Fox 1 and Fxh / Rbm9 , which encode an identical RRM . ^^^ |
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Interacting proteins: Q99700 and Q9NWB1 |
Pubmed |
SVM Score :0.0 |
A2BP1 encodes a protein that is known to interact with the spinocerebellar ataxia type 2 ( SCA 2 ) protein . ^^^ |
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