| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| In cultured hippocampal neurons , Homer family members Homer 1 , Cupidin / Homer 2 and Homer 3 showed similar glutamate induced declustering . ^^^ |
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| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| Expression of the Homer 1 mRNAs reaches 66 % of the brain total Homer mRNAs expression , followed by Homer 3 mRNA ( 22 % ) and Homer 2 mRNAs ( 12 % ) . ^^^ |
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| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| The existence of the long and the short variants of each of the Homer 1 , Homer 2 and Homer 3 proteins reflects the fundamental principles of Homer functions . . ^^^ |
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| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| Here , we report that deletion of Homer 1 or Homer 2 in mice caused the same increase in sensitivity to cocaine induced locomotion , conditioned reward , and augmented extracellular glutamate in nucleus accumbens as that elicited by withdrawal from repeated cocaine administration . ^^^ |
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| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| When expressed in HEK293T cells , 2B28 showed colocalization with uniquitin and enhanced the expression levels of IkappaB or Homer1a proteins , which are known to be degraded by proteasomes , indicating that 2B28 is involved in ubiquitin proteasome functions . 2B28 specifically interacted and colocalized with Homer 2 proteins , but not with Homer 1 proteins . ^^^ |
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| Interacting proteins: Q9NSB8 and Q86YM7 |
Pubmed |
SVM Score :0.0 |
| The purpose of this study is to determine whether single nucleotide polymorphisms in the Homer 1 and Homer 2 genes associate with the cocaine dependent phenotype in an African American population . ^^^ METHODS : This study utilized a case control design in which the genotype and allele frequencies for four single nucleotide polymorphisms in the Homer 1 gene and three single nucleotide polymorphisms in the Homer 2 gene were compared between African American individuals with a diagnosis of cocaine dependence ( n=170 ) and African American individuals with no history of substance abuse ( n=90 ) . ^^^ CONCLUSIONS : The results of this study suggest that a polymorphism in the Homer 1 gene , rs 6871510 , is a potential risk factor for the development of cocaine dependence in an African American population , whereas polymorphisms in the Homer 2 gene are not . . ^^^ |
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