| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.69102023 |
| The present study shows that DISC 1 participates in neurite outgrowth through its interaction with FEZ 1 . 0.69102023^^^ |
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| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.55201891 |
| In cell and animal models , C terminus truncated DISC 1 disrupts intracellular transport , neural architecture and migration , perhaps because it fails to interact with binding partners involved in neuronal differentiation such as fasciculation and elongation protein zeta 1 ( FEZ 1 ) , platelet activating factor acetylhydrolase , isoform Ib , PAFAH1B1 or lissencephaly 1 protein ( LIS 1 ) and nuclear distribution element like ( NUDEL ) . 0.55201891^^^ |
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| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.59700603 |
| Recently , we reported that FEZ 1 interacts with Disrupted In Schizophrenia 1 ( DISC 1 ) , a product of the candidate gene for schizophrenia , and that the interaction between these proteins has a role in neurite outgrowth . 0.59700603^^^ |
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| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.90629533 |
| In previous studies FEZ 1 has been found to interact with protein kinase Czeta , DISC 1 , the agnoprotein of the human polyomavirus JC virus , and E4B , a U box type ubiquitin protein isopeptide ligase . 0.90629533^^^ |
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| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.0 |
| We recently identified FEZ 1 as an interacting partner for DISC 1 . ^^^ CONCLUSIONS : A modest association between FEZ 1 and schizophrenia suggests that this gene and the DISC 1 mediated molecular pathway might play roles in the development of schizophrenia , with FEZ 1 affecting only a small subset of Japanese schizophrenia patients . . ^^^ |
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| Interacting proteins: Q99689 and Q9NRI5 |
Pubmed |
SVM Score :0.0 |
| Recent studies have suggested that DISC 1 plays a role in neuronal outgrowth , possibly through reported interactions with the molecules Nudel and FEZ 1 . ^^^ |
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