| Interacting proteins: Q9NRF2 and Q16620 |
Pubmed |
SVM Score :0.0 |
| In this report , we describe the identification and characterization of two substrates of Trk kinases , rAPS and SH 2 B , which are closely related Src homolog 2 ( SH 2 ) domain containing signaling molecules . rAPS and SH 2 B are substrates of TrkB and TrkC in cortical neurons and SH 2 B is a substrate of TrkA in sympathetic neurons . ^^^ |
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| Interacting proteins: Q9NRF2 and Q16620 |
Pubmed |
SVM Score :0.0 |
| Association of SH 2 B to phosphorylated tyrosine residues in the activation loop of TrkB . ^^^ Here we describe molecular cloning of human SH 2 B alpha , PH and SH 2 domain containing adaptor protein , as a TrkB binding protein , and how SH 2 B alpha associate with the cytoplasmic domain of TrkB at phosphorylated tyrosine residues in the kinase activation loop . ^^^ |
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| Interacting proteins: Q9NRF2 and Q16620 |
Pubmed |
SVM Score :0.0 |
| Overexpression of SAP with Trk attenuated tyrosine phosphorylation of the receptors and reduced the binding of SH2B and Shc to TrkB . ^^^ |
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