| When coexpressed in human embryonic kidney 293 cells , PrRP receptor was able to coimmunoprecipitate the three PDZ domain proteins known to interact with AMPA receptors : glutamate receptor interacting protein ( GRIP ) , AMPA binding protein ( ABP ) , and protein that interacts with C kinase ( PICK 1 ) , but not the PDZ domain protein PSD 95 , which does not interact with AMPA receptors . 1.1132491^^^ Furthermore , we show that PrRP receptor forms intracellular clusters when coexpressed with PICK 1 , and that this clustering effect is dependent on the interaction between the PICK 1 PDZ domain and the last four amino acids of PrRP receptor . 0.90751105^^^ |