| Interacting proteins: Q9NQC7 and Q9Y4K3 |
Pubmed |
SVM Score :0.80907641 |
| The tumor suppressor cylindromatosis ( CYLD ) acts as a negative regulator for toll like receptor 2 signaling via negative cross talk with TRAF 6 AND TRAF 7 . 0.80907641^^^ |
|
| Interacting proteins: Q9NQC7 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| The inhibition of NF kappaB activation by CYLD is mediated , at least in part , by the deubiquitination and inactivation of TNFR associated factor 2 ( TRAF 2 ) and , to a lesser extent , TRAF 6 . ^^^ |
|
| Interacting proteins: Q9NQC7 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| Recent studies have identified the tumor suppressor CYLD , loss of which causes a benign human syndrome called cylindromatosis , as a key negative regulator for NF kappaB signaling by deubiquitinating tumor necrosis factor ( TNF ) receptor associated factor ( TRAF ) 2 , TRAF 6 , and NEMO ( NF kappaB essential modulator , also known as IkappaB kinase gamma ) . ^^^ In addition , TRAF 2 and TRAF 6 appear to be differentially involved in NF kappaB dependent induction of CYLD by TNF alpha and NTHi . ^^^ |
|
| Interacting proteins: Q9NQC7 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| NA |
|