| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| We describe the isolation and functional characterization of a full length cDNA for one of the novel genes , designated breast cancer metastasis suppressor 1 ( BRMS 1 ) , which maps to human chromosome 11q13 . 1 q13 . 2 . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Identification and characterization of the murine ortholog ( brms 1 ) of breast cancer metastasis suppressor 1 ( BRMS 1 ) . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Breast cancer metastasis suppressor 1 ( BRMS 1 ) forms complexes with retinoblastoma binding protein 1 ( RBP 1 ) and the mSin 3 histone deacetylase complex and represses transcription . ^^^ Breast cancer metastasis suppressor 1 ( BRMS 1 ) suppresses metastasis of multiple human and murine cancer cells without inhibiting tumorigenicity . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| BRMS 1 ( breast cancer metastasis suppressor 1 ) was recently identified as a novel breast cancer metastasis suppressor gene . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Breast cancer metastasis suppressor 1 ( BRMS 1 ) transfected MDA MB 435 cells were examined for modifications of phosphoinositide signaling as a potential mechanism for metastasis suppression . 435 / BRMS1 cells expressed < 10 % of phosphatidylinositol 4 , 5 bisphosphate compared with parental cells , whereas levels of the PtdIns ( 4 ) P and phosphatidylinositol 3 phosphate were unchanged . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Breast cancer metastasis suppressor 1 ( BRMS 1 ) functions as a metastasis suppressor gene in breast cancer and melanoma cell lines , but the mechanism of BRMS 1 suppression remains unclear . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Suppression of murine mammary carcinoma metastasis by the murine ortholog of breast cancer metastasis suppressor 1 ( Brms 1 ) . ^^^ The murine ortholog ( Brms 1 ) of human breast cancer metastasis suppressor 1 shares 95 % identity to the human metastasis suppressor , BRMS 1 , in amino acid structure . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| The BRMS 1 ( breast cancer metastasis suppressor 1 ) gene has been found to suppress metastasis in animal models without inhibiting primary tumor growth . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| Breast cancer metastasis suppressor 1 ( BRMS 1 ) is stabilized by the Hsp 90 chaperone . ^^^ Breast cancer metastasis suppressor 1 ( BRMS 1 ) is a member of the mSin 3 HDAC transcription co repressor complex . ^^^ |
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| Interacting proteins: Q5PSV4 and Q9HCU9 |
Pubmed |
SVM Score :0.0 |
| NA |
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