| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| The Na current ( INa ) was moderately decreased ( about 10 % ) in LPa 2 neuron , but a 50 % reduction of the peak Ca current ( ICa ) was observed . ^^^ CAP ( 150 microM , 10 min ) highly attenuated the long lasting component of the inward current in LPa 2 recorded in Na free ( TEA ) Ba solutions . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| The effects of the Na , K pump inhibitor ouabain on the depth of depression of cholinosensitivity of defensive behavior command neurons LPa 2 , LPa 3 , RPa 3 , and RPa 2 were studied in the common snail using a cellular analog of habituation ; the role of intracellular Ca2+ in these effects was analyzed . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Generation and analysis of mice deficient in each of LPA 1 , LPA 2 , S1P1 , S1P2 , and S1P3 have provided valuable information on the in vivo roles of these receptors . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Flow cytometric and immunoblot analyses indicate that immature as well as mature DCs express the LPL receptors S1P1 , S1P3 , S1P5 , and LPA 2 , but not S1P2 , S1P4 , LPA 1 , or LPA 3 . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| More recently , the EDG receptors have been divided into two subfamilies : the lysophosphatidic acid subfamily , which includes LPA 1 , ( EDG 2 / VZG 1 ) , LPA 2 ( EDG 4 ) , and LPA 3 ( EDG 7 ) , and the sphingosine 1 phosphate receptor subfamily , which includes S1P1 ( EDG 1 ) , S1P2 ( EDG 5 / H218 / AGR16 ) , S1P3 ( EDG 3 ) , S1P4 ( EDG 6 ) , and S1P5 ( EDG 8 / NRG 1 ) . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Lysophosphatidic acid ( 1 acyl 2 lyso sn glycero 3 phosphate ; LPA ) and sphingosine 1 phosphate ( S1P ) are bioactive phospholipids which respectively act as agonists for the G protein coupled lpA receptors ( LPA 1 , LPA 2 , and LPA 3 ) and s1p receptors ( S1P1 , S1P2 , S1P3 , S1P4 , and S1P5 ) , collectively referred to as lysophospholipid receptors ( lpR ) . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NHERF 2 specifically interacts with LPA 2 receptor and defines the specificity and efficiency of receptor mediated phospholipase C beta 3 activation . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| We also found that LPA 2 interacts with Na+ / H+ exchanger regulatory factor 2 ( NHERF 2 ) . ^^^ Activation of Akt and Erk1 / 2 was significantly attenuated by silencing of NHERF 2 expression by RNA interference , suggesting a pivotal role of NHERF 2 in LPA 2 mediated signaling . ^^^ |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9HBW0 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
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