| Interacting proteins: Q9HAP2 and Q9Y2B0 |
Pubmed |
SVM Score :0.0 |
| Here we describe a novel protein MSAP ( MIR interacting saposin like protein ) that is a positive regulator of neurite outgrowth . ^^^ MSAP is a novel MIR interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain . ^^^ MSAP interacts with the ezrin radixin moesin ( ERM ) like myosin regulatory light chain interacting protein ( MIR ) , and the two proteins are co localized in cell lines and in primary neurons . ^^^ The stimulation of neurite outgrowth by MSAP was abrogated by the overexpression of MIR , which induced a decrease in the levels of myosin regulatory light chain ( MRLC ) . ^^^ This reduction in MRLC by MIR was inhibited by blocking the activity of proteasome and by overexpression of MSAP , suggesting an effect on protein stability . ^^^ |
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| Interacting proteins: Q9HAP2 and Q9Y2B0 |
Pubmed |
SVM Score :0.0 |
| Here we show that MRLC interacting protein ( MIR ) interacting saposin like protein ( MSAP ) enhances cell spreading in fibroblasts and migration of rat C 6 glioma cells through increases in MRLC phosphorylation . ^^^ |
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