| Interacting proteins: Q9H2G4 and O14936 |
Pubmed |
SVM Score :0.64248916 |
| CINAP , via its interaction with CASK , forms a complex with Tbr 1 , regulating expression of the genes controlled by Tbr 1 and CASK , such as NR2b and reelin . 0.64248916^^^ Here , we report that CASK binds to another nuclear protein , CINAP , which binds histones and facilitates nucleosome assembly . 0.61588116^^^ |
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| Interacting proteins: Q9H2G4 and O14936 |
Pubmed |
SVM Score :0.0 |
| CASK interacting nucleosome assembly protein ( CINAP ) modulates gene expression and its abundance in cultured neurons is regulated by synaptic activity . ^^^ |
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| Interacting proteins: Q9H2G4 and O14936 |
Pubmed |
SVM Score :0.0 |
| These proteins , whose interactions with CASK are reviewed here , include the Parkinson ' s disease molecule parkin , the adhesion molecule neurexin , syndecans , calcium channel proteins , the cytoplasmic adaptor protein Mint 1 , Veli / mLIN 7 / MALS , SAP 97 , caskin and CIP 98 , transcription factor Tbr 1 , and nucleosome assembly protein CINAP . ^^^ Among these interactions , CASK , Tbr 1 , and CINAP can form a transcriptional complex regulating gene expression . ^^^ Regulation of reelin and NR2b expression suggests the potential roles of the Tbr 1 CASK CINAP complex in neural activity , development , and disease . ^^^ |
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