| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| In this study , we demonstrate that human Cdt 1 is a substrate of Cdk 2 and Cdk 4 both in vivo and in vitro . ^^^ |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| It is recruited to chromatin by the origin recognition complex ( ORC ) , Cdc 6 , and Cdt 1 , and it is activated at the G ( 1 ) / S transition by Cdc 45 and the protein kinases Cdc 7 and Cdk 2 . ^^^ |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| Overexpression of the replication initiation factors Cdt 1 and Cdc 6 along with cyclin A cdk 2 promotes rereplication in human cancer cells with inactive p 53 but not in cells with functional p 53 . ^^^ |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| Here , we use Xenopus egg extracts to show that the recruitment of cohesins to chromosomes requires fully licensed chromatin and is dependent on ORC , Cdc 6 , Cdt 1 and MCM 2 7 , but is independent of Cdk 2 . ^^^ |
|
| Interacting proteins: Q9H211 and P24941 |
Pubmed |
SVM Score :0.0 |
| Using phosphopeptide mapping and mutagenesis studies , we found that threonine 29 within the N terminus of Cdt 1 is phosphorylated by Cdk 2 and required for interaction with Skp 2 . ^^^ |
|