| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| The anaphase promoting complex is composed of eight protein subunits , including BimE ( APC 1 ) , CDC 27 ( APC 3 ) , CDC 16 ( APC 6 ) , and CDC 23 ( APC 8 ) . ^^^ |
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| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| It has been reported , however , that vertebrate APC is composed of at least eight subunits , APC 1 to APC 8 , while budding yeast APC is constituted of at least 12 components , Apc 1 to Apc 13 . ^^^ |
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| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| Mnd 2 interacted strongly with Cdc 23 , Apc 5 , and Apc 1 when coexpressed in an in vitro transcription / translation reaction . ^^^ |
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| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| Of these , 32 sites are clustered in parts of Apc 1 and the tetratricopeptide repeat ( TPR ) subunits Cdc 27 , Cdc 16 , Cdc 23 and Apc 7 . ^^^ |
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| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| Seven core subunit homologs of APC / C ( APC 1 , APC 2 , APC 11 , CDC 16 , CDC 23 , CDC 27 , and DOC 1 ) were identified in the Trypanosoma brucei genome data base . ^^^ |
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| Interacting proteins: Q9H1A4 and Q9UJX2 |
Pubmed |
SVM Score :0.0 |
| We found that the largest subunit , Apc 1 , serves as a scaffold that associates independently with two separable subcomplexes , one that contains Apc 2 ( Cullin ) , Apc 11 ( RING ) , and Doc1 / Apc10 , and another that contains the three TPR subunits ( Cdc 27 , Cdc 16 , and Cdc 23 ) . ^^^ Apc 4 , Apc 5 , Cdc 23 , and Apc 1 associate interdependently , such that loss of any one subunit greatly reduces binding between the remaining three . ^^^ |
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