| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| The anaphase promoting complex is composed of eight protein subunits , including BimE ( APC 1 ) , CDC 27 ( APC 3 ) , CDC 16 ( APC 6 ) , and CDC 23 ( APC 8 ) . ^^^ |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| Of these , 32 sites are clustered in parts of Apc 1 and the tetratricopeptide repeat ( TPR ) subunits Cdc 27 , Cdc 16 , Cdc 23 and Apc 7 . ^^^ |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| Depletion of anaphase promoting complex or cyclosome ( APC / C ) subunit homolog APC 1 or CDC 27 of Trypanosoma brucei arrests the procyclic form in metaphase but the bloodstream form in anaphase . ^^^ Seven core subunit homologs of APC / C ( APC 1 , APC 2 , APC 11 , CDC 16 , CDC 23 , CDC 27 , and DOC 1 ) were identified in the Trypanosoma brucei genome data base . ^^^ Only the CDC 27 and APC 1 depleted cells were enriched in the G2 / M phase with inhibited growth . ^^^ Further studies indicated that T . brucei APC 1 and CDC 27 failed to complement the corresponding deletion mutants of budding yeast . ^^^ However , their depletion from procyclic form T . brucei enriched cells with two kinetoplasts and an enlarged nucleus possessing short metaphase like mitotic spindles , suggesting that APC 1 and CDC 27 may play essential roles in promoting anaphase in the procyclic form . ^^^ |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| We found that the largest subunit , Apc 1 , serves as a scaffold that associates independently with two separable subcomplexes , one that contains Apc 2 ( Cullin ) , Apc 11 ( RING ) , and Doc1 / Apc10 , and another that contains the three TPR subunits ( Cdc 27 , Cdc 16 , and Cdc 23 ) . ^^^ |
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| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| We also show that both the Tsg 24 protein and the Cdc 27 protein , another APC component , are bound to isolated mitotic chromosomes . ^^^ |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9H1A4 and P30260 |
Pubmed |
SVM Score :0.0 |
| NA |
|