| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| RIP 2 interacted with other members of the TNFR 1 signaling complex , including inhibitor of apoptosis protein cIAP 1 and with members of the TNFR associated factor ( TRAF ) family , specifically TRAF 1 , TRAF 5 , and TRAF 6 , but not with TRAF 2 , TRAF 3 , or TRAF 4 . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| TRAF 1 , TRAF 2 , TRAF 3 , and TRAF 6 , but not TRAF 4 or TRAF 5 , bound directly to the CD 40 cytoplasmic domain . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| In contrast to TRAF 2 and TRAF 3 , direct binding of TRAF 1 , TRAF 4 , TRAF 5 , or TRAF 6 to CD 40 was not detected . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| TRAF 2 p75 ( NTR ) , TRAF 4 p75 ( NTR ) , and TRAF 6 p75 ( NTR ) interactions modulated p 75 ( NTR ) induced cell death and NF kappaB activation with contrasting effects . ^^^ TRAF 4 also inhibited the NF kappaB response , whereas TRAF 2 and TRAF 6 enhanced p 75 ( NTR ) induced NF kappaB activation . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| Gp 39 treatment lowered the expression of TNFR associated factors TRAF 4 and TRAF 6 by 38 % and 32 % , respectively , whereas detectable levels of TRAF 1 , 2 , 3 , and 5 levels remained unchanged . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| All three HD cell lines showed strong expression of TRAF 2 protein and moderate , comparatively equal expression of TRAF 4 and TRAF 6 . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| Specific TRAF 4 and TRAF 6 precursor genes were found to have arisen earlier during evolution , with the divergence of the TRAF 6 precursor occuring earliest of all . ^^^ TRAF C domain homology indicated that dTRAF 3 is likely to have derived from the common precursor for the TRAF 1 , 2 , 3 and 5 genes , whilst dTRAF 1 and dTRAF 6 have derived from the TRAF 4 and TRAF 6 precursor genes , respectively . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| MUL and USP 7 are capable of binding in vitro via their TDs to all of the previously identified TRAF family proteins ( TRAF 1 , TRAF 2 , TRAF 3 , TRAF 4 , TRAF 5 , and TRAF 6 ) , whereas the TD of SPOP interacts weakly with TRAF 1 and TRAF 6 only . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| We carried out comparative in situ hybridization analysis of five Traf genes Traf 1 , Traf 2 , Traf 3 , Traf 4 and Traf 6 during murine odontogenesis from the formation of the epithelial thickening to the early bell stage . ^^^ Expression of Traf 1 , Traf 4 and Traf 6 were detected in the dental papilla mesenchyme . ^^^ Traf 2 showed restricted expression in the internal enamel epithelium of the bell stage while expression of Traf 1 , Traf 3 , Traf 4 and Traf 6 were observed in both the internal and the external enamel epithelium . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| TRAF 4 acts as a silencer in TLR mediated signaling through the association with TRAF 6 and TRIF . ^^^ |
|
| Interacting proteins: Q9BUZ4 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| NA |
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