| Sequence specific transcriptional repression by an MBD 2 interacting zinc finger protein MIZF . ^^^ We have recently identified a novel zinc finger protein , MIZF , as an MBD 2 binding partner . ^^^ To understand the physiological function of MIZF in MBD 2 mediated gene silencing , we investigated the DNA binding properties of MIZF and its potential target genes . ^^^ These results suggest that MIZF , through its DNA binding activity , acts as a sequence specific transcriptional repressor likely involved in MBD 2 mediated epigenetic gene silencing . . ^^^ |