Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q9BQA5 and Q9UBB5 Pubmed SVM Score :0.93854974
A direct interaction between MBD 2 and MIZF was confirmed by in vitro binding assays and immunoprecipitation experiments . 0.93854974^^^ Four of seven zinc fingers present in the C terminal region of MIZF are required for binding with MBD 2 . 0.82127218^^^
Interacting proteins: Q9BQA5 and Q9UBB5 Pubmed SVM Score :0.0
Sequence specific transcriptional repression by an MBD 2 interacting zinc finger protein MIZF . ^^^ We have recently identified a novel zinc finger protein , MIZF , as an MBD 2 binding partner . ^^^ To understand the physiological function of MIZF in MBD 2 mediated gene silencing , we investigated the DNA binding properties of MIZF and its potential target genes . ^^^ These results suggest that MIZF , through its DNA binding activity , acts as a sequence specific transcriptional repressor likely involved in MBD 2 mediated epigenetic gene silencing . . ^^^