| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| In this study orthologues of eight human PRMT genes ( PRMT 1 7 and HRMT1L3 ) were identified in both puffer fish Fugu rubripes and zebrafish Danio rerio . ^^^ HRMT1L3 is a PRMT 1 paralogue with highly conserved sequences and exact exon junctions , whereas the PRMT 2 orthologues are very diverged . ^^^ All other PRMT genes including PRMT 1 , 2 , 3 , 4 , 6 , 7 and HRMT1L3 clustered in the other branch , probably represent the genes for the type 1 activity . . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| Surprisingly , GST PRMT 7 was not able to catalyze the in vitro methylation of a GST fibrillarin ( amino acids 1 148 ) fusion protein ( GST GAR ) , a methyl accepting substrate for the previously characterized PRMT 1 , PRMT 3 , PRMT 4 , PRMT 5 , and PRMT 6 enzymes . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| Although GST fusions of PRMT 1 and PRMT 3 were also capable of methylating the full length HMGA1a polypeptide , they recognize its proteolytic degradation products much better . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| PRMT 2 directly bound and interacted with RB through its AdoMet binding domain , in contrast to other PRMT proteins , including PRMT 1 , PRMT 3 and PRMT 4 . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| Using purified recombinant protein arginine methyltransferases ( PRMTs ) , we showed that the C terminal domain could be methylated by PRMT 1 , PRMT 3 , and PRMT 4 in vitro and that both the R ( 544 ) K mutant and the R ( 546 ) K mutant were refractory toward these enzymes . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| Two terminators , pRMT 1 and pRMT 3 , are found within and around the D loop and cytochrome b gene , respectively , while the third , pRMT 5 , is located at the 3 ' end of the 16S ribosomal RNA gene . ^^^ After subcloning into host cells which carried temperature sensitive mutations in the termination factor , rho protein , galactokinase assays at the permissive and non permissive temperatures suggested that pRMT 3 acted as a rho independent termination element while the other two , pRMT 1 and pRMT 5 , were dependent on rho protein ( or a rho like protein ) for efficient transcription termination . . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| PRMT 3 , a type 1 protein arginine N methyltransferase that differs from PRMT 1 in its oligomerization , subcellular localization , substrate specificity , and regulation . ^^^ However , rat PRMT 1 and PRMT 3 glutathione S transferase fusion proteins have distinct enzyme specificities for substrates present in both hypomethylated rmt 1 yeast extract and hypomethylated RAT 1 embryo cell extract . ^^^ TIS 21 protein modulates the enzymatic activity of recombinant GST PRMT 1 fusion protein but not the activity of GST PRMT 3 . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| Unusual sites of arginine methylation in Poly ( A ) binding protein 2 and in vitro methylation by protein arginine methyltransferases PRMT 1 and PRMT 3 . ^^^ Poly ( A ) binding protein 2 and deletion mutants expressed in Escherichia coli were in vitro substrates for two mammalian protein arginine methyltransferases , PRMT 1 and PRMT 3 , with S adenosyl L methionine as the methyl group donor . ^^^ Both PRMT 1 and PRMT 3 specifically methylated arginines in the C terminal domain corresponding to the naturally modified sites . . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| At least four distinct mammalian family members have now been described , including PRMT 1 , PRMT 3 , CARM1 / PRMT4 , and JBP1 / PRMT5 . ^^^ We found that we could distinguish PRMT family members by their sensitivity to these reagents ; JBP1 / PRMT5 and Hsl 7 methyltransferases were inhibited in a similar manner as PRMT 3 , whereas Rmt 1 , PRMT 1 , and CARM1 / PRMT4 were not affected . ^^^ |
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| Interacting proteins: O60678 and Q99873 |
Pubmed |
SVM Score :0.0 |
| NA |
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