| Interacting proteins: Q99626 and P24941 |
Pubmed |
SVM Score :0.0 |
| Cdk 2 dependent phosphorylation of homeobox transcription factor CDX 2 regulates its nuclear translocation and proteasome mediated degradation in human intestinal epithelial cells . ^^^ These data suggest that CDX 2 undergoes CRM 1 dependent nuclear export and cytoplasmic degradation in cells in which Cdk 2 is activated , such as in proliferative intestinal epithelial cells . ^^^ The targeted degradation of CDX 2 following its phosphorylation by Cdk 2 identifies a new mechanism through which CDX 2 activity can be regulated in coordination with the cell cycle machinery . . ^^^ |
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| Interacting proteins: Q99626 and P24941 |
Pubmed |
SVM Score :0.0 |
| Crosstalk between the cell cycle regulator Cdk 2 and the Cdx 2 tumor suppressor at the proliferation differentiation interface . ^^^ |
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