| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Digestion of G 2 or G with a mixture of neuraminidase ( EC 3 . 2 . 1 . 18 ) , beta galactosidase ( EC 3 . 2 . 1 . 23 ) , and beta N acetylglucosaminidase ( EC 3 . 2 . 1 . 30 ) , however , produced a protein of molecular weight 65 , 000 . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Neuraminidase ( EC 3 . 2 . 1 . 18 ) beta galactosidase ( EC 3 . 2 . 1 . 23 ) and beta N acetylglucosaminidase ( EC 3 . 2 . 1 . 30 ) were studied in normal and regenerating rat liver . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Lysosomal neuraminidase ( sialidase ; EC 3 . 2 . 1 . 18 ) and beta galactosidase ( EC 3 . 2 . 1 . 23 ) , together with a carboxypeptidase , the so called ' protective protein ' , were co purified from the human placenta by affinity chromatography on a concanavalin A Sepharose column followed by a thiogalactoside agarose affinity column for beta galactosidase . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The accumulations of GM 3 and GD1a are considered to be the result of defective lysosomal sialidase activity and the accumulation of GM 1 , LacCer and GA 1 is also considered to be due to decreased beta galactosidase activity in this disorder . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| In the lysosome , the glycosidases neuraminidase ( EC 3 . 2 . 1 . 18 ) and beta galactosidase ( EC 3 . 2 . 1 . 23 ) are associated to a 52 kDa `` protective protein ' ' to form a large multi enzymatic complex . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Lysosomal sialidase deficiency in sialidosis with partial beta galactosidase deficiency . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The role of lysosomal sialidase and beta galactosidase in processing the complex carbohydrate chains on lysosomal enzymes and possibly other glycoproteins . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Carrier detection of sialidosis with partial beta galactosidase deficiency by the assay of lysosomal sialidase in lymphocytes . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The ras and the sis oncogenes increased beta galactosidase activities which were induced either by metal ( cadmium and zinc ) or by glucocorticoid ( dexamethasone ) , whereas the neu oncogene repressed its activity . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The lyso Pc inducible beta galactosidase of B lymphocytes and the Neu 1 sialidase of T lymphocytes were required for conversion of vitamin D 3 binding protein ( Gc protein ) to a potent macrophage activating factor . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The lyso Pc inducible beta galactosidase of B lymphocytes and the Neu 1 sialidase of T lymphocytes modified bovine DBP ( bDBP ) to yield the macrophage activating factor , a protein with N acetylgalactosamine as the remaining sugar . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The accumulated evidence suggests that lyso Pc inducible beta galactosidase of B lymphocytes and the Neu 1 sialidase of T lymphocytes modified the bovine serum vitamin D 3 binding protein ( DBP ) to yield the MAF , a protein with N acetylgalactosamine as the remaining sugar . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| To evaluate the potential efficacy of retrovirally transduced DCs , bone marrow cells harvested from BALB / c mice were transduced with either a model antigen gene encoding beta galactosidase ( beta gal ) or a control gene encoding rat HER 2 / neu ( Neu ) by coculture with irradiated ecotropic retroviral producer lines . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Cathepsin A [ EC 3 . 4 . 16 . 1 ] , so called protective protein , occurs as an enzyme complex with lysosomal beta galactosidase [ 3 . 2 . 1 . 23 ] and is involved in the stable enzymic expression of lysosomal sialidase [ 3 . 2 . 1 . 18 ] . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Lysosomal sialidase occurs in a multienzyme complex that also contains beta galactosidase and cathepsin A . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Transfectants expressing neu at a high level exhibited altered morphology and behavior in two dimensional and three dimensional culture in Matrigel , could be cloned in soft agar , and were more invasive through a Matrigel membrane than control transfectants transduced with a similar retrovirus expressing the beta galactosidase gene . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Galactosialidosis is an inherited lysosomal storage disease caused by the combined deficiency of lysosomal sialidase and beta galactosidase secondary to the deficiency of cathepsin A / protective protein , which is associated with sialidase and beta galactosidase in a high molecular weight ( 1 . 27MDa ) complex . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Three acidic glycosidases : beta galactosidase ( beta GAL , EC 3 . 2 . 1 . 23 ) , alpha neuraminidase ( NEUR , sialidase , EC 3 . 2 . 1 . 18 ) , N acetylaminogalacto 6 sulfate sulfatase ( GALNS , EC 3 . 1 . 6 . 4 ) and serine carboxypepidase cathepsin A ( EC 3 . 4 . 16 . 1 ) form a functional high molecular weight complex in the lysosomes . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Sialidosis and galactosialidosis are lysosomal storage diseases caused by the genetic defects of lysosomal sialidase ( neuraminidase 1 ; NEU 1 ) and lysosomal protective protein / cathepsin A ( PPCA ) , respectively , associated with a NEU 1 deficiency , excessive accumulation of sialylglycoconjugates , and development of progressive neurosomatic manifestations ; in addition , the latter disorder is accompanied by simultaneous deficiencies of beta galactosidase and cathepsin A . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| Regulation of the supramolecular organization and the catalytic activity of GM 1 galactosidase ( EC 3 . 2 . 1 . 23 ) and neuraminidase ( EC 3 . 2 . 1 . 18 ) from human kidney was studied in a system of hydrated reversed micelles of Aerosol OT in octane . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| This protein forms a high molecular weight complex with the hydrolases beta galactosidase ( GLB 1 ) and neuraminidase ( NEU 1 ) . ^^^ These data confirm that PPCA is present in two functional complexes one with GLB 1 and NEU 1 in the lysosomal lumen and the other with EBP at the cell surface . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| GLB 1 forms a complex with protective protein cathepsin A ( PPCA ) , alpha neuraminidase ( NEU 1 ) , and galactosamine 6 sulphate sulfatase ( GALNS ) inside lysosomes , while EBP binds to PPCA and NEU 1 on the cell surface . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| The purpose of this study is to determine effects of GLB 1 , PPCA and NEU 1 gene mutations on elastogenesis in skin fibroblasts . ^^^ Apparently normal elastogenesis and EBP mRNA expression were observed for fibroblasts from Morquio B disease cases with the GLB 1 gene alleles ( W273L / W273L , W273L / R482H and W273L / W509C substitutions , respectively ) , a galactosialidosis case with the PPCA allele ( IVS7+3A / IVS7+3A ) and a sialidosis case with the NEU 1 allele ( V217M / G243R ) as well as normal subject . ^^^ |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16278 and Q99519 |
Pubmed |
SVM Score :0.0 |
| NA |
|