| Interacting proteins: Q96QT4 and P04083 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of annexin 1 by TRPM 7 channel kinase . ^^^ Here we have identified annexin 1 as a substrate for TRPM 7 kinase . ^^^ Phosphorylation of annexin 1 by TRPM 7 kinase is stimulated by Ca2+ and is dramatically increased in extracts from cells overexpressing TRPM 7 . ^^^ Phosphorylation of annexin 1 by TRPM 7 kinase occurs at a conserved serine residue ( Ser 5 ) located within the N terminal amphipathic alpha helix of annexin 1 . ^^^ The N terminal region plays a crucial role in interaction of annexin 1 with other proteins and membranes , and therefore , phosphorylation of annexin 1 at Ser 5 by TRPM 7 kinase may modulate function of annexin 1 . . ^^^ |
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| Interacting proteins: Q96QT4 and P04083 |
Pubmed |
SVM Score :0.0 |
| Translocation of annexin 1 , specific TRPM 7 substrate , was measured as an index of TRPM 7 activation . [ Mg2+ ] 1 was determined using mag fura 2 . ^^^ |
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| Interacting proteins: Q96QT4 and P04083 |
Pubmed |
SVM Score :0.0 |
| NA |
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