| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| Although biochemical and genetic analyses in lower eukaryotes showed that Dicer and some PIWI family member proteins are essential for long dsRNA dependent PTGS , little is known about the molecular mechanisms underlying siRNA based PTGS . ^^^ Here , we show that Dicer and eIF2C translation initiation factors belonging to the PIWI family ( eIF2C1 4 ) play an essential role in mammalian siRNA mediated PTGS , most probably through synergistic interactions . ^^^ Immunoprecipitation experiments suggest that , in human and mouse cells , complex formation occurs between Dicer and eIF2C1 or 2 and that the PIWI domain of eIF2C is essential for the formation of this complex . . ^^^ |
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| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer . ^^^ PAZ PIWI domain ( PPD ) proteins , together with the RNA cleavage products of Dicer , form ribonucleoprotein complexes called RNA induced silencing complexes ( RISCs ) . ^^^ Rather , a subregion of the PIWI domain in PPD proteins , the PIWI box , binds directly to the Dicer RNase 3 domain . ^^^ |
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| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| Human dicer : purification , properties , and interaction with PAZ PIWI domain proteins . ^^^ PAZ and PIWI domain ( PPD ) proteins , also involved in RNAi and miRNA function , are the best characterized proteins known to interact with Dicer . ^^^ |
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| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| PPD ( PAZ Piwi domain ) proteins and the Dicer family have been the subjects of intense study over the last 6 years . ^^^ |
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| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96J94 and Q9UPY3 |
Pubmed |
SVM Score :0.0 |
| NA |
|