| Interacting proteins: Q96FA3 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| Pellino 1 is required for interleukin 1 ( IL 1 ) mediated signaling through its interaction with the IL 1 receptor associated kinase 4 ( IRAK 4 ) IRAK tumor necrosis factor receptor associated factor 6 ( TRAF 6 ) complex . ^^^ We now report a mammalian counterpart of Pellino , termed Pellino 1 , which is required for NF kappa B activation and IL 8 gene expression in response to IL 1 , probably through its signal dependent interaction with IRAK 4 , IRAK , and the tumor necrosis factor receptor associated factor 6 ( TRAF 6 ) . ^^^ |
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| Interacting proteins: Q96FA3 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate for the first time that human Pellino 2 interacts with TRAF 6 ( tumor necrosis factor receptor associated factor 6 ) and that both Pellino 1 and Pellino 2 also interact with TAK 1 ( transforming growth factor beta activated kinase 1 ) . ^^^ |
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| Interacting proteins: Q96FA3 and Q9Y4K3 |
Pubmed |
SVM Score :0.0 |
| NA |
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