| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| These conformational changes are mediated by a phosphorylation promoted interaction of the hydrophobic motif with a channel on the N terminal lobe induced by the ordered alphaC helix and are mimicked by peptides corresponding to the hydrophobic motif of PKB and potently by the hydrophobic motif of PRK2 . . ^^^ |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| This 40 kDa protein , designated PRAS 40 , is a proline rich Akt substrate . ^^^ Demonstration that it is a substrate of Akt was accomplished by showing that 1 ) PRAS 40 was phosphorylated in vitro by purified Akt on the same site that was phosphorylated in insulin treated cells ; 2 ) activation of an inducible Akt was alone sufficient to stimulate the phosphorylation of PRAS 40 ; and 3 ) cells lacking Akt 1 and Akt 2 exhibit a diminished ability to phosphorylate this protein . ^^^ Thus , PRAS 40 is a novel substrate of Akt , the phosphorylation of which leads to the binding of this protein to 14 3 3 . . ^^^ |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96B36 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|