| Interacting proteins: Q969H0 and P49768 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q969H0 and P49768 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q969H0 and P49768 |
Pubmed |
SVM Score :0.79122104 |
| In this study , we show that human SEL 10 interacts with PS 1 and enhances PS 1 ubiquitination , thus altering cellular levels of unprocessed PS 1 and its N and C terminal fragments . 0.79122104^^^ SEL 10 interacts with presenilin 1 , facilitates its ubiquitination , and alters A beta peptide production . 0.75819382^^^ |
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| Interacting proteins: Q969H0 and P49768 |
Pubmed |
SVM Score :0.0 |
| The Caenorhabditis elegans F box protein SEL 10 and its human homolog have been proposed to regulate LIN 12 Notch signaling by targeting for ubiquitin mediated proteasomal degradation LIN 12 Notch proteins and SEL 12 PS 1 presenilins , the latter of which have been implicated in Alzheimer ' s disease . ^^^ |
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