| Interacting proteins: Q969H0 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q969H0 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q969H0 and P46531 |
Pubmed |
SVM Score :0.0 |
| Expression of Notch 1 , 2 , or 3 or of cyclin E was unaffected in Fbw 7 ( / ) embryos . ^^^ |
|
| Interacting proteins: Q969H0 and P46531 |
Pubmed |
SVM Score :0.0 |
| Functional interaction between SEL 10 , an F box protein , and the nuclear form of activated Notch 1 receptor . ^^^ We isolated human and murine counterparts of SEL 10 and investigated the role of a dominant negative form of this protein , deleted of the F box , on Notch 1 stability and activity . ^^^ We then demonstrated that SEL 10 specifically interacts with nuclear forms of Notch 1 and that this interaction requires a phosphorylation event . ^^^ |
|
| Interacting proteins: Q969H0 and P46531 |
Pubmed |
SVM Score :0.0 |
| Expression of dominant negative SEL 10 leads to stabilization of the intracellular domain of Notch 1 . ^^^ Ubiquitination of Notch 1 and Notch 4 intracellular domains in vitro was dependent on SEL 10 . ^^^ Although SEL 10 interacts with the intracellular domains of both Notch 1 and Notch 4 , these proteins respond differently to interference with SEL 10 function . ^^^ |
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