| Interacting proteins: O15151 and Q93009 |
Pubmed |
SVM Score :0.80485497 |
| Further insight into the mechanism by which ATM switches the interactions between HAUSP , Mdmx , Mdm 2 and p 53 , to favor p 53 activation may offer new tools for therapeutic intervention in the p 53 pathway for cancer treatment . . 0.80485497^^^ |
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| Interacting proteins: O15151 and Q93009 |
Pubmed |
SVM Score :0.0 |
| Factors such as HAUSP , p 14 ( ARF ) , and MdmX play important regulatory roles in p 53 ubiquitination / deubiquitination and their interplay with Mdm 2 and p 53 compound layers of complexity for regulating this important pathway . . ^^^ |
|
| Interacting proteins: O15151 and Q93009 |
Pubmed |
SVM Score :0.0 |
| The discoveries of MdmX , HAUSP , ARF , COP 1 , Pirh 2 , and ARF BP 1 continue to uncover the multiple facets of this pathway . ^^^ |
|
| Interacting proteins: O15151 and Q93009 |
Pubmed |
SVM Score :0.0 |
| Herein , we deal with the post translational regulation of p 53 via its specific ubiquitinating enzymes ( Mdm 2 , Mdmx , COP 1 , Pirh 2 , ARF BP1 / Mule , and CHIP ) and a deubiquitinating enzyme , herpesvirus associated ubiquitin specific protease ( HAUSP ) . ^^^ |
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