| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| Four members of the tumor necrosis factor ( TNF ) ligand family , TNF alpha , LT alpha , LT beta , and LIGHT , interact with four receptors of the TNF / nerve growth factor family , the p 55 TNF receptor ( CD120a ) , the p 75 TNF receptor ( CD120b ) , the lymphotoxin beta receptor ( LT beta R ) , and herpes virus entry mediator ( HVEM ) to control a wide range of innate and adaptive immune response functions . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| An inhibitor protein of LIGHT and LT alpha beta 2 ( LT beta R Ig ) and an inhibitor protein of LIGHT ( HVEM Ig ) caused similar decreases in alloresponses of control B 6 or B6 . 129S1 IL12rb2 ( tm1Jm ) ( B6 . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| The following genes were overexpressed in both hyperplasia and adenoma : CHEK 1 , ATM , BCL XL , FAS , TNF , cIAP 1 , TRAIL , FADD , CASP 4 , 5 , 6 , 8 , CD120b , CD 137 , LTA , TANK , TARF 2 , CAD , LIGHTR , DR3LG . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| BTLA bound the most membrane distal cysteine rich domain of HVEM , distinct from regions where the ligands LIGHT and lymphotoxin alpha bound HVEM . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| The recently described tumor necrosis factor ( TNF ) family member LIGHT ( herpes virus entry mediator [ HVEM ] L / TNFSF14 ) , a ligand for the lymphotoxin ( LT ) beta receptor , HVEM , and DcR 3 , was inactivated in the mouse . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| In addition to gD binding to HveA , the latter has been shown to interact with proteins of tumor necrosis factor receptor associated factor family , lymphotoxin alpha ( LT alpha ) , and a membrane associated protein referred to as LIGHT . ^^^ When we analyzed these peptides for the ability to interfere with HveA binding to its natural ligand LT alpha , we found that BP 1 inhibited the interaction of cellular LT alpha with HveA . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| The three HveA receptor ligands , gD , LT alpha and LIGHT bind to distinct sites on HveA . ^^^ The herpes virus entry mediator A ( HveA ) , a member of the tumor necrosis factor receptor ( TNFR ) superfamily , interacts with three different protein ligands ; lymphotoxin alpha ( LT alpha ) and LIGHT ( LIGHT stands for lymphotoxin homolog , which exhibits inducible expression and competes with HSV glycoprotein D for HveA and is expressed on T lymphocytes ) from the host and the herpes simplex virus ( HSV ) surface glycoprotein gD . ^^^ Two HveA peptide ligands ( BP 1 and BP 2 ) that differentially inhibit binding of soluble gD and LT alpha to the receptor were also used to demonstrate that gD , LIGHT and LT alpha bind to distinct sites on the receptor . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| Lymphotoxins ( LT alpha and LT beta ) , LIGHT [ homologous to LT , inducible expression , competes with herpes simplex virus ( HSV ) glycoprotein D for HSV entry mediator ( HVEM ) , a receptor expressed on T lymphocytes ] , tumor necrosis factor ( TNF ) , and their specific receptors LT beta R , HVEM , and TNF receptor 1 ( TNFR 1 ) and TNFR 2 , form the immediate family of the larger TNF superfamily . ^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.92424958 |
| Here , we demonstrate that HVEM binds two cellular ligands , secreted lymphotoxin alpha ( LTalpha ) and LIGHT , a new member of the TNF superfamily . 0.92424958^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :1.3162123 |
| Here we show that HVEM binds BTLA with high affinity and can form a ternary complex with its known ligands homologous to lymphotoxin , showing inducible expression , and competing with herpes simplex virus glycoprotein D for HVEM , a receptor expressed by T lymphocytes ( LIGHT ) or lymphotoxin alpha and BTLA . 1.3162123^^^ |
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| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P01374 and Q92956 |
Pubmed |
SVM Score :0.0 |
| NA |
|