| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| Three unusual repair deficiencies associated with transcription factor BTF 2 ( TFIIH ) : evidence for the existence of a transcription syndrome . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| A protein kinase activity that phosphorylates the C terminal domain ( CTD ) of RNA polymerase 2 and is associated with the basal transcription repair factor TFIIH ( also called BTF 2 ) resides with MO 15 , a cyclin dependent protein kinase that was first found to be involved in cell cycle regulation . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF 2 ( TFIIH ) . ^^^ The recent finding that its gene product is identical to the p 89 subunit of basal transcription factor BTF 2 ( TFIIH ) , opened the possibility that it is not directly involved in NER but that it regulates the transcription of one or more NER genes . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| The human BTF 2 ( TFIIH ) transcription factor is a multisubunit protein involved in transcription initiation by RNA polymerase 2 ( B ) as well as in DNA repair . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| In addition , delta ' s human homolog , BTF 2 ( TFIIH ) , was recently shown to have an associated DNA helicase activity ( Schaeffer , L . , Roy , R . , Humbert , S . , Moncollin , V . , Vermeulen , W . , Hoeijmakers , J . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of the heptapeptide repeats in the C terminal domain ( CTD ) of the largest subunit of RNA polymerase 2 has been widely proposed as an essential step in transcription initiation on the basis of findings indicating ( 1 ) that the CTDs of RNA polymerase 2 molecules actively engaged in transcription are highly phosphorylated ; ( 2 ) that polymerase molecules containing non phosphorylated CTDs preferentially enter the preinitiation complex where they are subsequently phosphorylated ; and ( 3 ) that essential initiation factors b from yeast , delta from rat , and BTF 2 ( TFIIH ) from human cells have closely associated CTD kinase activities . ^^^ |
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| Interacting proteins: Q13888 and Q92759 |
Pubmed |
SVM Score :0.0 |
| NA |
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