| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| Analysis of the role of TFIIE in basal transcription and TFIIH mediated carboxy terminal domain phosphorylation through structure function studies of TFIIE alpha . ^^^ To study this function of TFIIE in more detail , systematic deletion mutations were introduced into the large subunit of TFIIE ( TFIIE alpha ) and were analyzed with regard to their effects on TFIIH dependent CTD phosphorylation , TFIIE dependent basal and enhancer dependent transcription , and interactions of TFIIE alpha with both TFIIE beta and TFIIH . ^^^ The amino ( N ) terminal half of TFIIE alpha , which possesses several putative structural motifs , was sufficient for the phosphorylation and transcription activities and for TFIIE beta interactions , whereas a site effecting both strong interactions with TFIIH and large stimulatory effects on transcription and CTD phosphorylation was localized to an acidic region near the carboxy ( C ) terminus . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| Using fluorescence in situ hybridization ( FISH ) , we show here that the genes encoding the TATA box binding protein ( TBP ) , TFIIB , TFIIE alpha , TFIIE beta , RAP 30 , RAP 74 and the 62 kDa subunit , of TFIIH are located at the human chromosomal bands 6q26 27 , 1p21 22 , 3q21 24 , 8p12 , 13q14 , 19p13 . 3 and 11p14 15 . 1 , respectively . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| We also show that TFIIH specifically phosphorylates three general transcription factors , human TFIID tau ( TBP ) , TFIIE alpha and TFIIF alpha ( RAP 74 ) . . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| In contrast , TFIIH preferentially phosphorylates the ctd as well as TFIIE alpha , but not cdk 2 . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| The large subunit of human TFIIE ( TFIIEalpha ) binds to and facilitates the enzymatic functions of TFIIH , but TFIIE also functions independently from TFIIH . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| General transcription factor IIH ( TFIIH ) is recruited to the preinitiation complex ( PIC ) through direct interactions between its p 62 ( Tfb 1 ) subunit and the carboxyl terminal domain of TFIIEalpha . ^^^ |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P29083 and Q92759 |
Pubmed |
SVM Score :0.0 |
| NA |
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