| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of three physiological substrates of protein kinase C ( PKC ) , MARCKS , neuromodulin ( Nm ) , and neurogranin ( Ng ) , was analyzed to determine their relative efficacy as substrates of PKC alpha , beta , and gamma and sensitivities to inhibition by calmodulin ( CaM ) and S 100 . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| MARCKS PSD was more potent than another widely used selective PKC substrate ( neurogranin ( ( 28 43 ) ) and was a good substrate for human recombinant PKC alpha , delta , and epsilon but not zeta . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| The effect of lipid moieties on activation of conventional ( PKC alpha and beta 1 ) , novel ( PKC delta ) and atypical ( PKC zeta ) PKC isoforms was evaluated in an in vitro assay , using biotinylated neurogranin as a substrate . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| The expression of PKC alpha and PKC delta in C 6 glioma cells was more abundant than NG 108 15 cells , however , PKC epsilon in NG 108 15 was more abundant than C 6 glioma cells in which PKC epsilon was almost undetectable . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| In a pigmented human melanoma line ( P MM 4 , 20 30 ng melanin / micrograms protein ) and its nonpigmented subclone ( NP MM 4 , undetectable melanin ) , PKC alpha mRNA was expressed in both , whereas PKC beta mRNA was detectable only in P MM 4 cells . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| Protein kinase C ( PKC ) isoforms epsilon and beta 2 were not significantly affected by T 3 , whereas PKC alpha was increased in whole cell lysates and in membrane fractions of cells incubated with 100 but not 50 ng T3 / ml . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| RESULTS : In NG , ET 1 stimulated cytosol to membrane translocation of PKC delta and PKC epsilon but not PKC alpha . ^^^ Platelet derived growth factor B did not cause translocation of PKC alpha , PKC delta , or PKC epsilon in either NG or HG . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| In HG at 48 h , increased total PKC alpha ( 222 + / 17 % of NG , P < 0 . 001 ) , beta 2 ( 209 + / 12 % , P < 0 . 001 ) , and epsilon ( 195 + / 19 % , P < 0 . 001 ) were observed . ^^^ In NG , tolrestat and ARI 509 exposure caused increased PKC activity , enhanced accumulation of total PKC alpha and beta 2 , with no change in total or fractional recovery of PKC delta or epsilon . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of RC 3 by PKC alpha , beta , or gamma was stimulated by Ca2+ , phospholipid , and diacylglycerol . ^^^ |
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| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92686 and P17252 |
Pubmed |
SVM Score :0.0 |
| NA |
|