| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.57439895 |
| Colocalization studies in transfected cells suggest that TNF R 55 forms a complex with FAN and that this complex recruits RACK 1 to the plasma membrane . 0.57439895^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| Because TNF RI DeltaTRID is retained at the cell surface , FAN may interact with the mutated receptor for a prolonged amount of time , thereby overactivating N SMase . ^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| By combined use of the yeast interaction trap system and a peptide scanning library , the novel WD repeat protein FAN has been identified , which specifically binds to a cytoplasmic nine amino acid binding motif of TNF R 55 . ^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| We have previously shown that a cytoplasmic region of TNF R 55 distinct from the death domain regulates the activation of N SMase through binding of the adapter protein FAN . ^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| Tumor necrosis factor ( TNF ) alpha induced neutral sphingomyelinase mediated generation of ceramide , a bioactive lipid molecule , is transduced by the adaptor protein FAN , which binds to the intracellular region of the CD120a TNFalpha receptor . ^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| In addition , using the yeast interaction trap system , we have identified one protein ( FAN ) that binds to the NSD and mediates activation of N SMase as well as seventeen other potential interaction partners of TNF R 55 . ^^^ |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92636 and P19438 |
Pubmed |
SVM Score :0.0 |
| NA |
|