Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
Mutant B cells , present in normal numbers , exhibited unimpaired BCR induced spleen tyrosine kinase ( Syk ) phosphorylation but reduced B cell linker protein ( BLNK ) phosphorylation , calcium flux , and nuclear factor kappaB ( NFkappaB ) , c jun N terminal kinase ( JNK ) , and extracellular signal regulated kinase ( ERK ) activation . ^^^ |
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Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
B cell receptor engagement in SLP 65 deficient B cell lymphoma cells also resulted in tyrosine phosphorylation of the proliferation and survival related MAPK 1 and STAT 5 molecules , which was sensitive to silencing of the SRC kinase LYN . ^^^ |
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Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
BNAS 2 was co precipitated with BASH as well as Btk and ERK 2 from a lysate of mouse B cell line . ^^^ Thus BNAS 2 may serve as a scaffold for signaling proteins such as BASH , Btk , and ERK at the ER and nuclear membrane and may facilitate ERK activation by signaling from cell surface receptors . . ^^^ |
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Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
When pre BCR was cross linked with anti micro heavy chain antibodies , significant phosphorylation of intracellular molecules , including Syk , Shc , ERK MAP kinase , and AKT , and an activation of Ras were observed without regard to deficiency of BLNK expression , suggesting that BLNK is not required for pre BCR mediated activation of MAP kinase and phosphatidyl inositol 3 ( PI 3 ) kinase signalling . ^^^ |
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Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
Intracellular calcium signaling and ERK activation in response to BCR engagement were also proportionately decreased and delayed , respectively , with stepwise reduction of plcgamma 2 dosage in a BLNK ( null ) background . ^^^ |
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Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q8WV28 and P28482 |
Pubmed |
SVM Score :0.0 |
NA |
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