| In addition , the BCOR complex contains components of a second ubiquitin E 3 ligase , namely , SKP 1 and FBXL 10 ( JHDM1B ) . ^^^ We show that BCOR coimmunoprecipitates isoforms of FBXL 10 which contain a JmjC domain that recently has been determined to have histone H3K36 demethylase activity . ^^^ |