Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The ATPase activity of cell extracts from 15 different mutants ( designated MA 1 , MA 2 , MA 3 , etc . ) was found to be at least 20 times less sensitive to aurovertin than that from the parent strain . ^^^ Aurovertin inhibited the energization brought about by addition of ATP to E . coli AN 180 membrane vesicles ; it was without effect on MA 1 and MA 2 membrane vesicles energized by ATP . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Two soluble preparations of human melanoma antigens ( MA 1 and MA 2 ) and one of a breast carcinoma ( BCA ) were prepared . ^^^ Spreading of monocytes from healthy donors was not inhibited by either MA 1 and MA 2 or BCA . ^^^ MA 1 and MA 2 significantly inhibited the spreading of monocytes from patients with melanoma , while monocytes from patients with other malignancies were not affected . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Seven monoclonal antibodies ( MAs ) against 55 kDa glycoprotein family of porcine zona pellucida ( ZP 3 ) reacting with either ZP 3 alpha ( MA 7 , MA 27 , MA 28 ) or ZP 3 beta ( MA 1 , MA 2 , MA 11 , MA 30 ) have been described . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
When TRA or TRC was a substrate , two products , MA 1 ( the major product ) and MA 2 from TRA , and one product , MC from TRC , were , respectively , detected in the methanol extract . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
We synthesized three peptides , MA 1 Thr 19 Val28 ( +Tyr ) , MA 2 Ser 807 Ala816 , and MA 3 Ser718 Glu 729 ( +Tyr ) from the sequence of Epstein Barr virus gp350 / 220 and immunized rabbits with these peptides . ^^^ Rabbit antisera to the peptides had antipeptide radioimmunoassay titers of 1 : 400 for anti MA 1 , 1 : 200 for anti MA 2 , and 1 : 1600 for anti MA 3 . ^^^ The anti MA 1 serum recognized gp350 / 220 in Western blotting to SDS electrophoresed proteins from 12 O tetradecanoylphorbol 13 acetate and n butyrate treated B 95 8 cells , but anti MA 2 and MA 3 sera did not . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
From urine of rats given the drug three metabolites ( MA 1 , MA 2 and MB 3 ) were isolated with structure shown in page 98 in addition to the parent compound ( MB 1 ) . ^^^ Preliminary observations showed that the toxicity and pharmacological activity of MB 3 , MA 2 and MA 1 decreased significantly compared with the parent drug XT . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Two distinct murine monoclonal antibodies , designated MA 1 and MA 2 , and limited proteolysis with thrombin and trypsin have been used to probe the structure of human platelet thrombospondin . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Both mutations in ma 1 ( 2170 ) and ma 2 ( 2172 ) are linked to the nit 1 gene coding for the nitrate reductase apoenzyme . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Each isolated proteolytic fragment of thrombospondins was then detected using either a radioimmunoassay with a polyclonal antibody or an enzyme linked immunosorbent assay with three monoclonal antibodies ( P 10 , MA 1 , MA 2 ) directed against different epitopes of whole platelet thrombospondin . ^^^ Monoclonal antibody MA 2 recognized three proteolytic fragments ( 54 47 , 25 20 , 18 15 kDa ) of endothelial and fibroblast ( 54 49 , 27 21 , 17 13 kDa ) thrombospondins , and two fragments ( 50 , 25 kDa ) of platelet thrombospondin , different from those detected by P 10 an MA 1 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Four ventilators ( Puritan Bennett MA 1 and MA 2 , Emerson , and Bear 1 ) and four commercially available disposable and nondisposable tubing circuits ( Bennett nondisposable , Becton Dickinson , Inspiron , and Life line ) were tested on a lung analog for differences in inspiratory circuit compression volume . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
N acetyl S 3 bromopropyl ( MA 1 ) , N acetyl S 3 chloropropyl ( MA 2 ) , N acetyl S 2 carboxyethyl ( MA 3 ) and N acetyl S 3 hydroxypropyl ( 1 ) cysteine ( MA 4 ) were synthesized and identified as metabolites in urine by g . l . c . mass spectrometry . 1 , 1 , 3 , 3 Tetradeutero 1 , 3 dibromopropane was used to study the mechanism of formation of the mercapturic acids in more detail . ^^^ At doses up to 30 mg of 1 , 3 DBP , excretion of mercapturic acids was virtually complete in 24 h urine and amounted to about 19 % of the dose ( 11 . 3 % MA 1 , 4 . 9 % MA 2 , 2 . 6 % MA 3 and 0 . 2 % MA 4 ) . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Live human and monkey sperm were agglutinated and immobilized by MA 1 but only immobilized by MA 2 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The mercapturic acids were identified as N acetyl S ( 1 phenyl 2 hydroxyethyl ) cysteine ( MA 1 ) and N acetyl S ( 2 phenyl 2 hydroxyethyl ) cysteine ( MA 2 ) . ^^^ The mercapturic acid , MA 1 , was excreted at higher rate than the isomer , MA 2 , on the administration of styrene and the phenyloxiranes . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
From the urine of rats , rabbits and humans treated with noscapine , two novel metabolites were isolated and identified as 7 hydroxy 6 methoxyphthalide ( MA 1 ) and 6 hydroxy 7 methoxyphthalide ( MA 2 ) , mainly by mass spectrometry . 2 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
These are : MA 1 , the adenine anion , probably protonated at N 3 ; MA 2 , the species formed by net hydrogen abstraction from the 9 methyl group ; and MA 3 , the radical formed by net hydrogen addition to C 8 of the adenine moiety . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Because the mechanism for this increase is unknown , we compared serum TSP levels in 11 patients to 15 controls using three different site specific monoclonal antibodies ( MA 1 , MA 2 and A6 . 1 ) . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Seven monoclonal antibodies ( MAs ) generated against porcine zona pellucida glycoprotein , ZP 3 ( comprising both ZP 3 alpha and ZP 3 beta ) were characterized for their specificities to ZP 3 alpha ( MA 7 and MA 28 ) or ZP 3 beta ( MA 1 , MA 2 , MA 10 , MA 27 and MA 30 ) and their relative affinities in competitive ELISA . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
After partial hydrolysis of ManLAM , two populations of mannans ( Ma 1 and Ma 2 ) were obtained by gel filtration chromatography . ^^^ They are highly branched , and Ma 2 presents a higher frequency of branching than Ma 1 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The peptides represented 20 amino acid segments between residues 111 and 130 ( MA 1 ) and residues 116 and 135 ( MA 2 ) of the p 19 gag proteins of HTLV 1 and HTLV 2 , respectively . ^^^ By using the ratio of the optical density of MA 1 to the optical density of MA 2 , which represents for every serum sample the ratio between the absorbance value obtained in the MA 1 assay and the absorbance value obtained in the MA 2 assay , 59 of the 69 reactive serum samples were clearly and easily typed as positive for either antibody to HTLV 1 or antibody to HTLV 2 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Four acidic metabolites were identified as the synthetic compounds : ( + ) ( 2S , 3S ) 3 ( acetyloxy ) 8 chloro 3 , 4 dihydro 2 ( 4 methoxyphenyl ) 4 oxo 1 , 5 benzothiazepin 5 ( 2H ) acetic acid ( MA 1 ) , deacetyl MA 1 ( MA 2 ) , O demethyl MA 1 ( MA 3 ) and deacetyl O demethyl MA 1 ( MA 4 ) ; and the two remaining acidic metabolites , MA 5 and MA 6 , were presumed to be hydroxylated MA 3 and MA 4 , respectively . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Virus MA 1 retained 5 amino acids of the extracellular domain and the complete transmembrane and intracellular domains of Axl ; virus MA 2 retained only the intracellular Axl sequences beginning 33 amino acids downstream of the transmembrane region . ^^^ MA 1 transformants became elongated and assumed a cross hatched pattern , while MA 2 transformants were round and very refractile and grew to high density . ^^^ However , MA 2 transformed NIH 3T3 cells , but not MA 1 or control cells , could establish sarcomas by subcutaneous or intraperitoneal injection into BALB / c neonates . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
These three species yielded a 2 : 1 mixture of N acetyl S ( 1 phenyl 2 hydroxyethyl ) cysteine ( MA 1 ) and N acetyl S ( 2 phenyl 2 hydroxyethyl ) cysteine ( MA 2 ) . ^^^ However , R styrene oxide yielded stereospecifically S , R MA 1 and R , R MA 2 whereas S styrene oxide gave R , R MA 1 and S , R MA 2 . ^^^ The ratios of R , R / S , R isomers were 80 : 20 and 15 : 85 for MA 1 and MA 2 , respectively . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Ma 2 shares homology with Ma 1 , a `` brain testis cancer ' ' gene related to other paraneoplastic syndromes and tumors . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The MA 1 and MA 2 neurons had similar synaptic effects on the jaw closing and opening motoneurons . ^^^ Simultaneously , spikes in one of the MA 1 neurons and the MA 2 also gave rise to monosynaptic excitatory postsynaptic potentials ( EPSPs ) in the ipsilateral jaw opening motoneuron . 3 . ^^^ The IPSPs and the EPSPs induced by spikes in the premotor neurons were reversibly blocked by d tubocurarine and hexamethonium , respectively , suggesting that the MA 1 and MA 2 neurons are cholinergic . 4 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The growth of Listeria monocytogenes and Yersinia enterocolitica colonies was studied on solid media at 4 and 8 degrees C under modified atmospheres ( MAs ) of 5 % O 2 : 10 % CO 2 : 85 % N 2 ( MA 1 ) , 30 % CO 2 : 70 % N 2 ( MA 2 ) and air ( control ) . ^^^ At 4 degrees C both MAs decreased the growth rates of L . monocytogenes by 1 . 5 and 3 . 0 fold under MA 1 ( mu = 0 . 02 h ( 1 ) ) and MA 2 ( mu = 0 . 01 h ( 1 ) ) , respectively , as compared with the control ( mu = 0 . 03 h ( 1 ) ) . ^^^ The time to detection of bacterial colonies was increased from 15 d ( control ) to 24 ( MA 1 ) and 29 d ( MA 2 ) . ^^^ At 4 degrees C both MAs decreased the growth rates of Y . enterocolitica by 1 . 5 and 2 . 5 fold under MA 1 ( mu = 0 . 03 h ( 1 ) ) and MA 2 ( mu = 0 . 02 h ( 1 ) ) , respectively , as compared with the control ( mu = 0 . 05 h ( 1 ) ) . ^^^ At 8 degrees C identical growth rates were obtained under MA 1 and the control ( mu = 0 . 07 h ( 1 ) ) whilst a decrease in the growth rate was obtained under MA 2 ( mu = 0 . 04 h ( 1 ) ) . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Antibodies to Ma 1 and Ma 2 proteins identify a paraneoplastic disorder that affects the limbic system , brain stem , and cerebellum . ^^^ Eleven patients had antibodies to Ma 2 and additional antibodies to Ma 1 and / or Ma 3 ; they usually developed additional cerebellar symptoms and more intense brainstem dysfunction , and 82 % of these patients had tumors other than germ cell neoplasms . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Based on analysis by high performance liquid chromatography ( HPLC ) , mass , and nuclear magnetic resonance ( NMR ) spectroscopic techniques , the structure of these metabolites were identified as 4beta hydroxymethyl 4beta demethylterritrem A ( MA 1 ) , 4beta oxo 4beta demethylterritrem A ( MAX ) , and 2 dihydro 4beta demethylterritrem A ( MA 2 ) . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Metabolism of TRA to 2 dihydro 4beta demethylterritrem A ( MA 2 ) through 4beta hydroxymethyl 4beta demethylterritrem A ( MA 1 ) and 4beta oxo 4beta demethylterritrem A ( MAX ) was observed in intact male rats . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
In an attempt to improve neuroreceptor distribution volume ( 5 ) estimates , the authors evaluated three alternative linear methods to Logan graphical analysis ( GA ) : GA using total least squares ( TLS ) , and two multilinear analyses , MA 1 and MA 2 , based on mathematical rearrangement of GA equation and two tissue compartments , respectively , using simulated and actual PET data of two receptor tracers , [ ( 18 ) F ] FCWAY and [ ( 11 ) C ] MDL 100 , 907 . ^^^ The bias reduction was most pronounced for MA 1 , moderate to large for MA 2 , and modest to moderate for TLS . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Further , Western blot analysis indicated that CYP3A2 protein was expressed in 2 wk old rats of both sexes and 7 wk old male rats , and 3 metabolites of TRA , such as MA 1 , MAX , and MA 2 , were formed using supersomes from CYP3A2 expressing baculovirus infected insect cells . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
Anti Ma 2 antibody related paraneoplastic limbic / brain stem encephalitis associated with breast cancer expressing Ma 1 , Ma 2 , and Ma 3 mRNAs . ^^^ The cerebrospinal fluid from the patient harboured an anti neuronal cell antibody against Ma 2 antigen , but not against Ma 1 or Ma 3 antigen . ^^^ Despite the antibody being restricted to the Ma 2 antigen , the patient ' s cancer tissue expressed Ma 1 , Ma 2 , and Ma 3 mRNAs . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The metabolites of territrems MA 1 , MAX , MA 2 , MB 2 , MB 4 , and MC were measured by high performance chromatography ( HPLC ) . ^^^ Formation of MA 1 , MAX , and MA 2 decreased after 52 wk in males , and MAX and MA 2 were not formed after 6 wk in females . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
ESTs 10 , P 12 , and MA 2 map to the N terminal domain ; 5G11 , TSP127 . 6 , and ESTs 12 to the third properdin module ; C6 . 7 , HB 8432 , and P 10 to epidermal growth factor ( EGF ) like modules 1 and / or 2 ; and A6 . 1 , mAb 133 , MA 1 , and D4 . 6 to the calcium binding wire module . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
At generation 265 , one of those MA 1 lines was expanded to start 150 new full sib MA 2 lines and a new C 2 large control . ^^^ After 46 generations , the rate of decline in mean viability in MA 2 was approximately 2 . 5 times that estimated in MA 1 , while the average degree of dominance of mutations was small and nonsignificant by generation 40 and moderate by generation 80 . ^^^ The results are consistent with a mutation rate in the line from which MA 2 and C 2 were derived about 2 . 5 times larger than that in MA 1 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
The MA is comprised of the first ( MA 1 ) , second ( MA 2 ) , and additional fine structural branches ; however , differences in terms of responsibilities of these branches have not been assessed . ^^^ This investigation revealed that MA 1 exhibits responsibilities similar to those of the aorta , whereas MA 2 possesses distinct responsibilities . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
High grade is defined as Bloom and Richardson grade 3 ( B & R 3 ) , Nottingham modification , or mitotic activity ( MAI ) > or =10 / 1 . 59 mm 2 . ^^^
Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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Interacting proteins: Q9UL42 and Q8ND90 Pubmed SVM Score :0.0
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