Interacting proteins: P35226 and Q8IXK0 |
Pubmed |
SVM Score :0.0 |
Here , we identify two human proteins , HPH 1 and HPH 2 , that are associated with the vertebrate PcG protein BMI 1 . ^^^ HPH 1 and HPH 2 coimmunoprecipitate and cofractionate with each other and with BMI 1 . ^^^ HPH 1 , HPH 2 , and BMI 1 show distinct , although overlapping expression patterns in different tissues and cell lines . ^^^ |
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Interacting proteins: P35226 and Q8IXK0 |
Pubmed |
SVM Score :0.0 |
The complex , termed hPRC1L ( human Polycomb repressive complex 1 like ) , is composed of several Polycomb group proteins including Ring 1 , Ring 2 , Bmi 1 and HPH 2 . hPRC1L monoubiquitinates nucleosomal histone H2A at lysine 119 . ^^^ |
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Interacting proteins: P35226 and Q8IXK0 |
Pubmed |
SVM Score :0.0 |
In previous studies , we identified the histone H2A ubiquitin ligase as Ring 2 , together in a complex with Ring 1 , Bmi 1 , and HPH 2 ( human polyhomeotic 2 ) . ^^^ |
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