| Human cellular protein VRK 2 interacts specifically with Epstein Barr virus BHRF 1 , a homologue of Bcl 2 , and enhances cell survival . ^^^ For BHRF 1 , aa 1 18 and 89 142 were crucial in interacting with VRK 2 and these two regions are counterparts of Bcl 2 homology domains 4 and 1 . ^^^ However , this enhancement was not observed when VRK 2 was co expressed with Bcl 2 . ^^^ |